Categories | Recombinant Serum Albumin |
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Brand Name: | Oryzogen |
Model Number: | HY100M1 |
Certification: | ISO 9001 certificate |
Place of Origin: | China |
MOQ: | Negotiation |
Price: | Negotiation |
Payment Terms: | T/T |
Supply Ability: | 1000kg |
Delivery Time: | 3~5 days |
Packaging Details: | 1g/vial 10g/vial 50g/vial |
Source: | Rice Grain (Oryza Sativa) |
Purity: | Great than 99% (Analysis by SDS-PAGE and HPLC) |
Formulation: | Lyophilized with saline |
Physical Appearance: | Off-white to light beige lyophilized powder |
Amino Acid Sequence: | Same as the HSA from plasma |
Product Type: | Recombinant Protein |
Description
As the most abundant protein in human plasma, HSA is composed of 585 amino acids. It has a molecular weight of 66.5KD and an isoelectric point of 4.8. rHSA is widely used in biochemical experiments, such as being used as a blocking ragent in western, also plays a role in mailly maintaining the osmotic pressure, PH buffer and as carriers and nutritions. rHSA can also be used as a hapten carrier, a protective reagent, and in protein complementation control in cell culture.
Healthgen uses State-of-the-art platform called OryzHiExp, having high capacity to express proteins and peptides in the rice grain. The platform uses rice endosperm cells as a bioreactor to specifically and highly express various recombinant proteins and small peptides. The platform is a rice-specific endosperm cell-specific expression platform that focuses on the expression of animal-free products, safe recombinant proteins and peptides. We use this technique to express recombinant human serum albumin to achieve higher safety and biosafety.
Physiological and Biochemical Properties of rHSA and pHSA
Char. | pHSA | rHSA |
Amino Acids Sequence | Same | Same |
N-terminus | DAHKSEV | DAHKSEV |
C-terminus | KLVAASQAALGL | KLVAASQAALGL |
Glycosylation | No | No |
Molecular Mass(MALDI) | 66.554KD | 66.550KD |
PI | 4.8 | 4.8 |
Drug Binding | Similar | Similar |
Thermal Stability | M/P 65℃ | M/P 65℃ |
Lipid Conjugation | Identical | Identical |
Crystal Structure | Identical | Identical |
Recombinant human serum albumin (rHSA) was lyophilized with saline and the physical appearance is off-white to light beige powder. The advantages of rHSA powder are as followed: First, the protein will not be denatured or loss its biological activity; Secondly, lyophilized products will be in the form of loose powder after drying and the color does not change. The lyophilized products can recover the original physical, chemical characteristics and biological activity of the aqueous solution after quickly dissolve in water. Third, since the lyophilized products are produced under vacuum conditions, some easily oxidizable materials will be protected well during the proceeding. Fourth, after freeze-dried, the products will stay in a lower moisture level, so that the stability of the products will increase while making contamination much less likely. This not only facilitates the transportation but also extends the storage time of the products.
Supplemental Description
Healthgen Biotechnology Corp. is a private company founded in 2006. We specialize in molecular pharmaceutical technology research and high-tech innovation-oriented product development, which is developing, manufacturing and marketing a series of recombinant proteins and growth factors by rice endosperm platform. We have 400 square meters of research center, in which 30% of the research personnels have doctoral degree and major in different directions of the research and development. Healthgen has strong capability in developing a series of biological products.