CAS 121062-08-6 Melanotan II
Product Name:Melanotan II,MT-2
CAS number: 121062-08-6
Molecular formula: C50H69N15O9
Molecular Weight: 1024.180
Purity : 98%
Appearance : White Powder
Grade : Pharmaceutical Grade
Many in the bodybuilding community have already heard of Melanotan
II (M2) and its amazing ability to promote darker skin
pigmentation. What many bodybuilders don’t realize is that
Melanotan II also comes with other added benefits that would be of
great interests to those on and off cycle. These can include weight
loss, increased libido and lean body mass.
For a bodybuilder planning to compete on stage, there is a
considerable amount of time and attention to detail committed
before they are ready to compete. Being muscled up and defined is
only accentuated by a nice tan to make lines and definitions pop
out and become more evident to viewers and judges. Enter the
heptapeptide Melanotan II, now bodybuilders can actually protect
themselves from over exposure to the sun while boosting melanin.
This results in a darker and more tanned complexion. When Melanotan
II is added to a peptide protocol leading up to a show, it will
boost melanin levels, resulting in tanner skin; in addition, it
will increase fat loss and muscle hardness.
In addition, central application of the MC3/4-R agonist
melanotan-II decreases body fat (increases lipolysis) beyond that
accounted for by its ability to decrease food intake.
What is Melanotan 2 ?
Melanotan 2 Tanning Injections (otherwise known as MT2) was first
synthesized at the University of Arizona. Researches there knew
that onc of the best defenses against skin cancer was melanin
activated in the skin, a tan. They hypothesized that an effective
way to reduce skin cancer rates in people would be to induce the
body's natural pigmentary system to produce a protective tan prior
to UV exposure. The body's naturally occuring hormone MSH causes
melanogenesis, a process by which the skin's pigment cells
(melanocytes) produce the skin's pigment (melanin). They tested to
see if administering this endogenous hormone to the body directly
could be an effective method to cause sunless tanning. What they
found was that while it appeared to work, natural MSH had too short
a half life in the body to be practical as a therapeutic drug. So
they decided to find a more potent and stable alternative, one that
would be more practical.
After synthesizing and screening hundreds of molecules, the
researchers headed by Victor J. Hruby and Mac E. Hadley, found a
peptide, [Nle4, D-Phe7] MSH, that was approimately 1,000 times more
potent than the natural MSH. They dubbed this new peptide molecule,
"Melanotan" (later Melanotan-1, now know as afamelanotide). They
subsequently developed another analog,
Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2), which they called
"Melanotan" Tanning Injections. The scientists hoped to use these
peptides to combat melanoma by stimulating the body's natural
pigmentary mechanism to create a tan without first needing exposure
to harmful levels of UV radiation. This in turn, they hypothesized,
could reduce the potential for skin damage that can eventually lead
to skin cancer.
A pilot phase I clinical trial conducted on three males by the
College of Medacine, Pharmacology Department, University of Arizona
in Tuscon, Arizona pulished in 1996 reported that, "Melanotan"
Tanning Injections has tanning activity in humans given only 5 low
doses every other day by subcutaneous injection." The side effects
reported were mild nausea and a "stretching and yawning complex"
that correlated with spontaneous penile erections.
The Department of Pharmacology, University of Arizona College of
Medacin published in 1998 that involved 10 men who suffered from
psychogenic erectile dysfunction. Their trial concluded that,
"Melanotan" Tanning Injections is a potent initiator of erections
in men with pyschogenic erectile dydfunction and has manageable
side effects at a dose of 0.025mg/kg.
A clinical study published in 2000 of 20 men with psychogenic and
organic erectile dysfunction conducted at the Section of Urology of
The University of Arizona College of Medacin concluded, "that
Melanotan II Tanning Injections is a potent initiator of penile
erection in men with ecrectile dysfunction.
How to use Melanotan 2
Mixing the solution
Flip off the cap from the Melanotan 2 Tanning Injection vial.
Wipe the surface of the top of the vial with the enclosed alcohol
wipe and discard the wipe.
Wipe the surface of the injectable water tube (or glass water vial
depending on the pack ordered) with the enclosed alcohol wipe and
discard the wipe.
Remove the enclosed syringe from the packaging. Making sure the
injectable water tube is upright, insert the needle of the syringe
into the sidewall of the water.
Now pull back the plunger of the syringe so you withdraw 1ml of
water and slowly pull the syringe out.
Insert the syringe into the Melanotan 2 Tanning Injection vial and
depress the plunger so you completely empty the syringe of the
water and slowly remove the syringe from the vial. Do not shake the
Place the Melanotan 2 solution in the fridge for storage until
ready for use.
Make sure you put the syringe caps on and carefully dispose of it.
You have now mixed your Melanotan 2 Tanning Injection solution.
Please store the solution in the fridge
How to use Melanotan II for tanning
Melanotan II is typically provided in vials containing 10 mg of
lyophilized (freeze-dried) powder. The vials are reconstituted with
a convenient amount of bacteriostatic or sterile water, added to
the vial by syringe. An example convenient amount of water is 2.5
mL. When this amount of water is used, the resulting solution
contains 4 mg of MT-II per mL. If for example wishing to take a
dose of 1 mg, a volume of 0.25 mL, or "25 IU" as marked on an
insulin syringe, would be taken by injection. Injection may be
subcutaneous, intramuscular, or intravenous, according to personal
Injection typically is only once per day, but where a person is
first trying the drug and judging tolerance, injection may be
divided into two smaller amounts per day.
Typical dosage range is 0.5 to 2.0 mg/day, with a preferred range
of 0.5 to 1.0 mg/day. However, it's best to first assess tolerance
with lower dosing of 0.25 mg at a time.
After reconstitution, a Melanotan II vial should preferably be
consumed entirely within 30 days. Prior to reconstitution, MT-II
should be stored in the refrigerator or freezer, but it's
acceptable for it to be shipped without refrigeration.
Use generally should be discontinued if MT-II, in the individual
case, causes problems with increased growth, number, or darkness of
Melanotan II's effect is fairly long-lasting. It can even be the
case that it takes a year or more for a cycle's effect to largely
disappear. Use of maintenance cycles can maintain effect
indefinitely. As a rule of thumb, maintenance typically requires
about 2 to 3 times as much MT-II per year as was needed for the
first cycle. This can be taken either as a total of 2 to 3 cycles
per year done in the same way as the initial cycle, or any more
frequent dosing pattern providing this total amount of MT-II per
Administering the Melanotan 2
Select a new syringe and pull the plunger right back to the maximum
Holding the Melanotan 2 Tanning Injection vial upright, insert the
syringe and depress the plunger fully (this is to equalise the air
pressure in the vial which makes it easier to take out the
Leaving the syringe in the Melanotan 2 Tanning Injection vial, turn
everything upside down.
Pull the plunger until you have 10 units/0.1 of Melanotan 2 in the
syringe and slowly remove it.
Find a fleshy area of your skin - 4cm to the side of your belly
button is the most common. Wipe the area with one of the alcohol
Pinch 2cm either side of the area to be injected.
Holding the syringe like a pen, and at 90 degrees to your skin,
swiftly insert the syringe into your skin.
Fully depress the plunger so all the Melanotan 2 has emptied from
the syringe and slowly withdraw.
Hold the alcohol wipe on the injected area for a minute.
You have now administered your first dose of Melanotan 2. Tanning
Dosages and Usage
Like every peptide we have discussed thus far, please remember that
peptides come in the form of a white delicate powder and should be
stored out of light in a cool dry place. All peptides need to be
reconstituted with bacteriostatic water or sodium chloride
specifically used for injections. In order to use Melanotan II
effectively, you need to understand your skin type. To keep things
simple, we can go ahead and break skin types into three categories.
Skin Type 1: Very fair skin, never tans. Dosages: 50-60mgs or
Skin Type 2: Fair skin, burns but sometimes tans. Dosages: 30-40mgs
or 3-4 vials.
Skin Type 3: Medium skin, sometimes burns and always tans. Dosages:
20mgs or 2 vials.
Beyond that, if your pigmentation is already naturally olive or
darker, you will need to use less Meanotan II for your tanning
needs. The tan results coupled with exposure to sunlight and UV
rays should last a user all summer or through a season.
Daily Dosages vary depending on your needs:
For Erectile Dysfunction (ED): average dose is around 0.025 mgs/kg
(1kg = 2.2 lbs)
For Tanning (skin pigmentation): average dose is 0.025-0.030 mgs/kg
(1kg = 2.2 lbs)
The side effects associated with Melanotan II are similar to other
peptides: flushed face, headache, feeling dizzy, lethargy, nausea,
white patches and possible soreness or redness at site of
injection. The benefits users get from Melanotan II are: darker
skin pigmentation, appetite suppression, fat loss, lean body mass,
increased libido and frequency of erections.
There is a serious anecdotal note about Melanotan II, some users
have experienced serious nausea after using M2. This is variable
from user to user, but has to be a concern. You need to feel out
your dosages and start slow before you go head long into using this
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Hot-selling peptides list :
|Melanotan I||10mg/vial ,10vial/box|
|Melanotan II||10mg/vial ,10vial/box|
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|cjc1295 dac||2mg/vial ,10vial/box|
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